PCA3 Test


What is the PCA3 test?

The PCA3 test is a new gene-based test that is performed on a urine sample. PCA3 stands for prostate cancer gene 3, a gene that is involved in the development of prostate cancer. This test is not a replacement for PSA testing, but provides an additional tool to help detect prostate cancer.

Unlike PSA, the PCA3 result is not elevated when a man suffers from a disease that increases the size of the prostate such as benign prostatic hyperplasia (BPH, i.e. prostate enlargement) or prostatitis (infection of the prostate). PCA3 is specific to prostate cancer. Therefore, it gives very useful information, in addition to PSA, in deciding if a biopsy is really needed.